Authors: Associate Professor Mahesh Thakare, Pooja Choudhary, Sakshi Harihar, Vijaykumar Kale, Associate professor Vaibhav Narwade
Abstract: Approximately 85% of teenagers suffer from acne vulgaris, which can last until adulthood. Teenagers see doctors approximately two million times a year, and the US spends more than $1 billion on acne treatments directly. There are many different therapy options for acne vulgaris, such as hormonal, anti- androgen, or anti seborrheic medications, as well as retinoids, isoprenoids, keratolytic soaps, alpha hydroxy acids, azelaic acid, and salicylic acid. All of these techniques do have some negative effects, though, and it's unclear exactly how they fit into therapy. This paper not only presents the potential causes of acne vulgaris, medications that can treat it, and recently released research on the usage of medicinal herbs to treat the condition were examined. Topical formulations (herbal cream) have been developed containing Ocimum sanctum (Tulsi) extract, Aloe barbadensis miller (Aloe-vera Gel), Melaleuca Oil (Tea Tree Oil). These medicinal herbs and essential oil (TTO) show anti-bacterial activity against acne causing bacteria like Propionibacterium and staphylococcus aures. Various batches containing above Herbs and Essential oil are prepared and their comparative studies are performed. Certain evaluation tests are performed like Irritancy, Washability, pH, Greasiness to check whether cream is suitable for human skin. In the end anti-bacterial activity of the cream was carried out using agar well diffusion method against staphylococcus aures.
DOI: http://doi.org/
