Authors: Rahmatulloh Tohirovich Saidov, Mavjuda Gafurovna Khudoerzoda, Akmal Ziyodulloevich Kholov, Shahrukh Nasrulloevich Nazarov, Dilnoza Mahmadaliyevna Qalandarova
Abstract: As genomic data repositories expand rapidly with the growing need for precision medicine and population-scale genomics, managing the integrity, security, and regulatory compliance of these repositories has become a paramount concern. This paper presents a compliance-centric approach to automating server infrastructure specifically tailored for genomic data management. We explore the integration of Unix-based server automation tools with security-first policies and standards such as HIPAA, GDPR, and ISO 27001. The study outlines how configuration management, access control automation, logging, and continuous compliance auditing are implemented to ensure operational resilience and regulatory alignment. By leveraging scripting, cron-based scheduling, and policy-as-code frameworks, genomic data infrastructures can be both scalable and secure. The proposed automation model reduces human error, enhances traceability, and allows for real-time response to compliance deviations, making it a critical foundation for modern biomedical computing environments.
