Real-ESRGAN–Driven MRI Super-Resolution For Diagnostic Precision And AI-Assisted Clinical Deployment

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Authors: Nupur Jadhav, Atharva Bhusnale, Pritesh Gupta, Sakshi Jadhav, Vaishali Hiray

Abstract: Magnetic Resonance Imaging (MRI) is very impor-tant in the detection of neurological defects because it possesses high resolution that enables good visualization of soft-tissue structure. However, diagnostic clarity is often hindered by low-resolution scans due to the short time of acquisition, motion artifacts and hardware constraints. Recent advances in deep learning, such as Enhanced Super-Resolution Generative Ad-versarial Networks (Real-ESRGAN), have demonstrated strong capabilities of perceptual-driven image enhancement.This paper discusses Real-ESRGAN-based MRI super-resolution strategies, their architectural advantages and clinical potential benefits, in preserving fine anatomical and pathological details much better than CNN-based and conventional interpolation methods. We also present a conceptual AI-enabled deployment framework, where Real-ESRGAN is handled by a clinician support chatbot for application in web-based interaction, tele-radiology accessibility and diagnostic help. Clinical validation including metrics such as PSNR, SSIM,LPIPS and sFRC is investigated. The study emphasizes the need for interpretable, regulation-ready models to bridge AI-driven MRI enhancement with real-world diagnostic workflows.

DOI: http://doi.org/10.5281/zenodo.20766158

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