Authors: Ali Akbar, Komal Sarwar
Abstract: Heavy metals, prevalent in various environmental matrices due to industrial and agricultural activities, pose significant health risks, including the promotion of cancer through the induction of oxidative stress. This paper reviews the mechanisms by which heavy metals such as arsenic, cadmium, chromium, and lead contribute to oxidative stress, leading to cellular damage and cancer development. We explore the complex interplay between heavy metal exposure, oxidative stress, and the activation of key signaling pathways involved in carcinogenesis. Understanding these mechanisms is crucial for developing effective strategies to mitigate the health impacts of heavy metal exposure and improve cancer prevention efforts.
DOI: https://doi.org/10.5281/zenodo.17424408
