Preparation Of Tradescantia Pallida Mediated Calcium Carbonate Nanoparticles And Their Activity Against Hela Cell Lines

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Authors: Akshita verma

 

Abstract: Purpose: To make calcium carbonate nanoparticles (CaCO₃NPs) and test their fluorescent and cytotoxic properties utilising Tradescantia pallida (Commelinaceae). Method: T. pallida aqueous leaf extract is used to make CaCO₃ NPs according to a straightforward technique (TPALE). Determine their crystalline nature and functional groups, Fourier transform infrared spectroscopy (FTIR) investigations are used. Photoluminescence characteristics of CaCO₃ Nanoparticles are evaluated using fluorescence spectroscopy. Following confirmation of CaCO₃ NP synthesis, the 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide (MTT) assay is used to assess cytotoxicity against HeLa cell line. Conclusion: On the basis of TPALE, a simple method for synthesising CaCO₃ NPs has been successfully established. The generated CaCO₃ NPs have good luminescent characteristics and are cytotoxic to a cancer cell line.

DOI: http://doi.org/ijsret.vol.11.issue3.152

 

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